Jobs at Kyverna Therapeutics

The Sr. Director, Clinical Scientist leads clinical research for Multiple Sclerosis therapies, overseeing study execution, protocol development, and cross-functional collaboration in a biotech setting.

Lead global regulatory strategy for Kyverna's cell therapy portfolio across development, approval, and commercialization. Drive labeling strategy, health authority engagements (FDA, EMA), regulatory submissions (INDs, BLAs/MAAs), and cross-functional alignment with Clinical, CMC, Commercial, Market Access, and Legal. Mentor and scale the regulatory team, manage external partners, and provide regulatory input for business development and portfolio decisions to enable launch readiness and lifecycle management.

Lead discovery and early development strategy for next-generation immune cell therapies. Oversee multidisciplinary teams, evaluate and advance in vivo CAR-T and cellular engineering technologies, build external collaborations, prioritize discovery investments, and partner with clinical, regulatory, and business teams to progress candidates from discovery through IND-enabling development.

Lead development and execution of CAR T channel strategy and operations, overseeing 3PL, specialty pharmacy, distribution, state licensing, government pricing support, GTN optimization, partner governance, launch readiness, reporting, and cross-functional coordination to ensure scalable, compliant commercialization.

Lead integrated lifecycle strategy for emerging therapeutic platforms from discovery through commercialization. Coordinate cross-functional teams (Research, Clinical, Regulatory, Manufacturing, Quality, Commercial) to drive INDs, pivotal studies, PV/PPQ, launch readiness, and lifecycle expansion. Define development pathways, manufacturing strategies, CDMO partnerships, and commercialization plans to maximize portfolio value and mitigate program risk.

Senior leader accountable for integrated development and commercialization strategy of CAR-T programs. Leads lifecycle governance, cross-functional coordination, portfolio prioritization, regulatory and manufacturing readiness, risk assessment, and executive-level decision-making to advance programs from development through regulatory filings and launch.

Lead cross-functional program management for engineered T cell therapy development. Translate strategy into integrated plans, track milestones and risks, drive execution and governance, align stakeholders, and build operational processes. May recruit and supervise junior PM staff.

Lead U.S. commercial sales and go-to-market strategy for CAR-T therapies. Build and scale a specialty sales organization, drive launches and market penetration, manage field teams, collaborate cross-functionally on access and site readiness, and use analytics to monitor KPIs and optimize performance.

The Senior Clinical Research Scientist will design, execute, and analyze clinical studies, ensuring compliance with GCP and regulatory requirements, and collaborate across multiple departments.

The Sr. Director of Business Development will drive Kyverna's growth strategy through strategic partnerships, licensing, and collaboration in the biopharmaceutical sector.