Jobs at Praxis Precision Medicines, Inc.

Own and evolve enterprise AWS infrastructure, governance, security, identity, networking, and shared platforms. Build and operate full-stack services in TypeScript and Python, automate infrastructure and delivery, improve monitoring and reliability, manage incidents and on-call operations, and establish audit-ready controls. Partner across engineering and IT, improve production readiness, and mentor engineers while delivering secure, scalable, low-blast-radius systems.

Lead the end-to-end development of a drug-device combination product from device design and verification through regulatory submission and launch. Own program strategy, timelines, risk management, design history file activities, FDA regulatory coordination, and cross-functional execution. Serve as the technical bridge between pharmaceutical and device teams, technology partners, consultants, and executives. Provide hands-on leadership across electronics, software, electrochemistry, delivery hardware, human factors, quality systems, and combination product compliance.

Build, configure, administer, and support enterprise SaaS applications, ERP/CRM integrations, SQL data models, ETL processes, and automated workflows. Diagnose production issues, improve reliability, manage testing and deployments, document systems, coordinate vendors, and partner with business, data, security, and validation teams to deliver dependable commercial applications.

Own and improve Snowflake platform operations across development, test, and production environments. Responsibilities include security and access governance, reliability engineering, monitoring, incident response, recovery procedures, consumption and cost optimization, change management, automated testing, and controlled releases. The role partners with Data Engineering, Security, Identity, AWS, and commercial technology teams while documenting processes and building reusable automation.

Leads the strategy, roadmap, delivery, reliability, and adoption of commercial IT systems supporting pharmaceutical launches and growth. Owns CRM, commercial data, field enablement, integrations, vendor performance, budgets, launch readiness, user acceptance testing, training, change management, compliance, and cross-functional stakeholder alignment across IT, Sales, Marketing, Commercial Operations, Market Access, Security, Legal, Privacy, and Quality.

Lead complex commercial and clinical-development contract negotiations while building and scaling Praxis’s contracting function. Establish templates, playbooks, governance, workflows, and a multi-year operating model. Provide practical legal and risk guidance to clinical, technical, commercial, finance, procurement, compliance, and other teams. Support clinical trial contracting, vendor risk assessment, privacy and regulatory matters, and responsible use of AI and legal technology to improve contracting efficiency.

Design and maintain scalable ETL/ELT pipelines, analytical dashboards, and reporting tools supporting clinical, research, and operational priorities. Write production-quality Python, R, and SQL; develop data architecture; partner with data scientists to operationalize analytics; integrate AI-enabled workflow improvements; establish engineering standards; and mentor junior team members.

Lead regional payer engagement across half the U.S., building trusted relationships with commercial plans, Medicaid programs, and regional Blue plans. Develop and execute account plans, communicate clinical and economic value, support utilization management aligned with label, gather regional payer intelligence to inform pricing and launch strategy, identify access barriers and solutions, collaborate cross-functionally, monitor policy and reimbursement trends, and support launch readiness. Role requires frequent travel and cross-functional influence.

Provide end-to-end product quality oversight for clinical and commercial programs (drug substance, drug product, packaging, labeling, external manufacturers). Review and approve critical quality documentation, lead investigations (deviations, OOS/OOT, CAPA), oversee vendor qualification and audits, support batch disposition and regulatory inspection readiness, and partner with CMC, Regulatory, and Supply Chain to manage quality risks and ensure reliable supply.

Lead national payer engagement with health plans, PBMs, GPOs to secure coverage, reimbursement, and access. Own national payer strategy, pricing, contracting, and Medicare Part D engagement. Drive payer-facing evidence and value communication, support launches, align cross-functionally, anticipate payer shifts, and represent Praxis as a thought leader.

Design and optimize field commercialization capabilities—KPIs, dashboards, incentive compensation, targeting/segmentation, vendor data management, and analytics—to support pre-launch, launch, and post-launch field effectiveness. Partner cross-functionally with Commercial Leadership, Sales, Market Access, Medical Affairs, Finance, IT, and Compliance to translate strategy into measurable execution frameworks and scalable processes.

Lead enterprise FP&A for a clinical-stage biotech, driving budgeting, forecasting, long-range planning, and resource allocation. Partner with program and functional leaders to evaluate investments, embed financial insight, advance reporting and AI/automation, conduct scenario analyses, and support accounting close to enable disciplined, high-impact decisions for commercialization.

Lead and develop a regional field sales team to execute commercial strategy and drive product launch performance. Coordinate with cross-functional partners (Commercial, Medical Affairs, Patient Services, Market Access) to ensure field readiness, KPI-driven performance, compliance, and delivery across pre-launch, launch, and post-launch phases.

Lead and develop a regional field sales organization to execute commercial strategy across pre-launch, launch, and post-launch phases. Drive team performance, KPI tracking, cross‑functional collaboration (Commercial, Medical Affairs, Market Access), and field insights while ensuring regulatory compliance and readiness for product launches.

Lead and develop a regional field sales team to execute commercial strategy across pre-launch, launch, and post-launch phases. Drive customer engagement with cross-functional partners, set KPIs, coach performance, ensure regulatory compliance, and provide field insights to inform commercial strategy.