Jobs at Revolution Medicines

Leads the enterprise strategy, operating model, technical standards, and delivery of real-world analytics and programming across the pharmaceutical product lifecycle. Oversees RWD assessment, RWE study design, statistical analysis, programming, reporting, regulatory support, advanced analytics, data pipelines, governance, resourcing, and team development. Partners with clinical, safety, regulatory, medical affairs, HEOR, market access, commercial, IT, and statistical functions to generate rigorous evidence for oncology development and commercialization decisions.

Leads cross-functional commercial project management within an assigned oncology disease area. Responsibilities include commercialization planning, launch readiness, governance, milestone and risk management, stakeholder alignment, executive communication, project reporting, and development of commercial project-management capabilities across global and regional teams.

Leads statistical programming for oncology real-world evidence studies from protocol and SAP review through final deliverables. Develops, validates, and maintains SAS, SQL, R, and Python solutions for cohort construction, endpoint derivation, analysis datasets, TLFs, survival analyses, propensity score methods, and sensitivity analyses. Partners with HEOR, RWE, data science, and biostatistics teams while assessing healthcare data quality, documenting reproducible workflows, managing multiple studies, and guiding junior programmers.

Develop and validate machine-learning models for drug discovery using chemical, biological, imaging, phenotypic, and structural datasets. Perform exploratory analysis, integrate heterogeneous data, build reproducible workflows, and communicate findings to medicinal chemists, biologists, and research scientists. Apply supervised, deep-learning, graph-based, and ensemble methods to support compound optimization, target discovery, screening, and translational research.

Lead analytics strategy for the company’s gastrointestinal oncology portfolio. Partner with Commercial, Medical Affairs, Market Access, Clinical Development, and Business Operations to generate insights from claims, EMR, physician, patient, and market data. Support portfolio strategy, launch readiness, commercialization planning, segmentation, patient journey analysis, competitive assessments, performance dashboards, and data strategy. Manage external analytics vendors and communicate strategic recommendations to senior leadership.

Leads specialty pharmacy channel operations for Revolution Medicines’ US market, including partner account management, launch readiness, operational processes, governance, performance monitoring, issue resolution, SOPs, data validation, and patient access improvement. Collaborates across Distribution, Patient Services, Market Access, Commercial Operations, Finance, Legal, Supply Chain, and Business Insights. Manages channel agreements, partner performance, training, and a high-performing team.

The Contract Manager will manage the full lifecycle of commercial, clinical, research, vendor, procurement, and technology agreements. Responsibilities include drafting, reviewing, redlining, negotiating, coordinating approvals, maintaining contract records and CLM data, supporting audit readiness, partnering with cross-functional stakeholders, escalating high-risk terms to counsel, and improving contracting processes through automation and AI-enabled tools.

Leads cross-functional commercialization and launch initiatives within an assigned disease area. Responsibilities include developing project plans, managing milestones, risks, dependencies, governance, dashboards, and executive communications; coordinating Commercial, Medical, Market Access, Regulatory, Supply, Legal, Finance, and regional stakeholders; supporting launch readiness and lifecycle planning; and advancing commercial project management capabilities, tools, and best practices.

Leads US and global marketing strategy, brand planning, launch readiness, customer insights, omnichannel promotion, partnerships, agency relationships, and cross-functional execution for an oncology PDAC portfolio. Builds relationships with medical affairs, sales training, clinical development, payers, providers, and external stakeholders while ensuring regulatory compliance and budget management. Requires extensive biotechnology or pharmaceutical commercial marketing experience, product launch expertise, and targeted oncology knowledge.

Leads global pricing strategy and execution for an oncology biopharmaceutical portfolio. Establishes pricing architecture, launch and lifecycle strategies, contracting guardrails, financial models, governance, dashboards, and local execution frameworks. Partners across market access, commercial, medical, finance, legal, regulatory, supply chain, and regional teams. Supports launch readiness, executive decision-making, and development of a high-performing global pricing organization.

Leads PDAC marketing strategy, brand planning, positioning, promotional and medical education initiatives for oncology product launches. Builds and manages a marketing team, develops strategic partnerships, collaborates with sales and field teams, engages healthcare stakeholders, manages budgets, and drives omnichannel growth. Requires extensive biotechnology or pharmaceutical commercial marketing experience, launch expertise, executive leadership, and strong cross-functional influence.

Manages global and domestic tax compliance and reporting, including VAT/GST, ASC 740 tax provisions, transfer pricing, income tax, sales and use tax, audits, tax credits, SEC disclosures, and SOX controls. Partners with internal finance teams and external advisors across multiple jurisdictions, supports international expansion, improves tax processes, and coordinates tax authority inquiries and documentation.

Leads U.S. commercialization operations, strategic and financial planning, governance, launch readiness, executive communications, organizational effectiveness, change management, and cross-functional alignment. Partners with senior leaders across marketing, field, market access, medical affairs, finance, legal, analytics, and global commercial operations. Builds scalable processes, dashboards, capabilities, and high-performing teams while ensuring compliant commercialization and fostering organizational culture.

Leads strategic planning, operational excellence, communications, and enterprise initiatives for the Market Access organization. Translates objectives into measurable plans, manages leadership operating cadences, coordinates KPIs and resources, oversees cross-functional programs, and supports executive decision-making. Partners with Commercial, Medical Affairs, HEOR, Finance, Legal, and Compliance to align market access priorities, improve execution, and support successful product launches and patient access.

Leads U.S. pharmaceutical strategic pricing and provider contracting, developing pricing analyses, financial models, gross-to-net forecasts, contract recommendations, and executive presentations. Oversees GPO, IDN, integrated health system, and government customer strategies while ensuring regulatory compliance. Partners with Finance, Legal, Market Access, Marketing, Forecasting, and Commercial leadership to evaluate access implications, support contract approvals, and prepare oncology pipeline assets for launch.

Leads global market research and insights for targeted oncology therapies, translating complex market, disease, competitive, and managed-care data into strategic recommendations. Supports portfolio, lifecycle, clinical development, and commercialization decisions across geographies. Partners with Commercial Development, Clinical Development, Portfolio Management, Medical Affairs, and analytics teams; manages research vendors; communicates findings to senior leadership; and strengthens organizational understanding of market dynamics and product opportunities.

Leads strategic and promotional marketing plans for pancreatic cancer oncology products, including launch readiness, brand strategy, customer segmentation, omnichannel content, market research, agency relationships, budgets, and cross-functional collaboration. Mentors marketing colleagues, ensures compliant execution, and informs lifecycle and portfolio strategy using disease-state, competitive, and market insights.

Lead revenue accounting and gross-to-net (GTN) close activities, forecasting, and controls for commercial launch readiness. Prepare journal entries, reconciliations, reserve rollforwards, and SOX-compliant processes. Build GTN models, partner with Commercial/Market Access and Analytics, manage government pricing coordination, develop dashboards and automation, support SEC reporting, and drive AI-enabled efficiency improvements.

Lead development and execution of marketing and launch strategies for Revolution Medicines' lung cancer programs. Collaborate cross-functionally with clinical, medical affairs, market access, analytics, and external agencies to shape promotional materials, stakeholder segmentation, and launch readiness. Mentor peers, manage agency relationships and budgets, ensure regulatory compliance, and measure marketing effectiveness to drive brand performance and patient adoption.

Lead global commercial development for oncology product teams: define indication and brand strategies, prepare global launch readiness, translate scientific and market insights into launch narratives and forecasts, build cross-functional alignment, manage external agencies, integrate digital/omnichannel approaches, and support early pipeline commercial assessments. Role requires strategic leadership and up to 50% travel.