Jobs at Vertex Pharmaceuticals

Provides senior administrative and office support for department leaders, including calendar management, meeting logistics, travel booking, expense reporting, purchasing, invoices, contracts, visitor registration, onboarding, and presentation preparation. Maintains office operations, supplies, budgets, and vendor relationships while coordinating with IT and facilities teams. Supports site-wide events, handles confidential information discreetly, and serves as a resource for internal business technologies.

Leads discovery immunology programs in autoimmune and inflammatory diseases, from therapeutic target identification and validation through mechanism-of-action studies and early drug discovery. Designs and interprets in vitro, ex vivo, and in vivo research, develops disease models and translational strategies, and applies immune profiling, flow cytometry, molecular analyses, and preclinical methods. Collaborates across biology, chemistry, computational, translational, and project teams; mentors scientists; and communicates findings through publications, presentations, and strategic program updates.

The role involves leading biomarker strategies in immunology, managing assay development and validation, mentoring teams, and communicating complex strategies to stakeholders.

Vertex is seeking a Seattle Research Site Head for Immunology to lead scientific projects, manage research functions, and shape strategies for immunology developments. The role demands strong leadership in advancing biologics and overseeing a research team, with responsibilities including partnerships and project management.

Lead Seattle laboratory technology operations and act as the accountable Research Site Partner. Manage site operating budget, vendor ecosystems, programs, and cross-site prioritization. Serve as product owner for site requirements, drive technology adoption and change management, ensure GxP/SOX-compliant IT/OT operations, and lead a local team with full people-management responsibility.

Lead design, execution, and optimization of spatial transcriptomics studies to characterize tissue architecture, cell interactions, and therapeutic response. Generate and integrate spatial data with single-cell, proteomic, imaging, and histologic datasets, develop robust sample and assay workflows, evaluate new spatial technologies, communicate findings, and mentor junior scientists to support discovery, translational, and biomarker programs.

Lead design, optimization, and execution of high-parameter flow cytometry assays and multicolor immunophenotyping. Integrate cytometry with molecular profiling, analyze complex data to inform translational hypotheses, establish best practices, troubleshoot assays, mentor junior staff, and drive cytometry workstreams across discovery and development programs.